CURRENT CLINICAL RESEARCH NEWS

Overactive Bladder News

1. Researchers to take 'unprecedented look' into protein behind hypertension, epilepsy, and overactive bladder

   The seemingly unrelated conditions of hypertension, epilepsy and overactive bladder may be linked by electrical activity in a protein long studied by a biomedical engineer at Washington University in St. Louis.

2. Researchers study how often healthcare providers prescribe anticholinergics for older adults

   Anticholinergics are a class of medications that are often prescribed for allergies, lung disease, and urinary incontinence. They also often can increase health risks for older adults.

3. Botulinum neurotoxin type X holds potential to open up new field of toxin therapeutics

   Botulinum toxins are currently used on more than 80 medical conditions including Muscle spasms, Overactive bladder, Chronic migraine, Cervical dystonia, Sweating and Cerebral Palsy (CP).

4. Identifying overactive bladder syndrome

   Unfortunately, studies show that only about 5 million people living with OAB seek care from a doctor, and only half of those patients seek a specialist like a urologist or urogynecologist for treatment. It’s time to see a doctor if you’re using multiple leakage pads per day, not doing things you like because of the fear of leakage, planning all your travel around bathroom locations, or are worried about the problem every day.

5. Researchers develop simple urine-based test for rapid and accurate detection of Zika virus

   There is no vaccine. No medication. And, no quick, reliable test for Zika virus … until now. Babies born with the virus often have lifelong, devastating birth defects.

6. Use of antimuscarinics linked to depressive disorder in women with overactive bladder

   A recent study found that women with overactive bladder who received antimuscarinics were 38% more likely to be diagnosed with depressive disorder within the next 3 years than those who did not receive antimuscarinics.

7. Bacterial infection may play role in causing OAB symptoms

   A team led by researchers at the University of Kent has identified bacterial infection as a possible cause of Overactive Bladder Syndrome (OAB).

8. Long-term suppression of neurotransmitter acetylcholine may lead to dementia-like changes in the brain

   A new study from Western University is helping to explain why the long-term use of common anticholinergic drugs used to treat conditions like allergies and overactive bladder lead to an increased risk of developing dementia later in life.

9. Antimuscarinic drugs effective in improving OAB symptoms

   In a recent study of patients with overactive bladder (OAB), a 30 mg extended release formulation of propiverine hydrochloride was at least as effective and safe as a 4 mg extended release formulation of tolterodine tartrate.

10. Cranberry capsules more effective in lowering UTI risk than juice

    A UTI is an infection in any part of the urinary system, kidneys, bladder or urethra. They are more common in women and affect more than 3 million Americans per year. Many in the population will turn to sipping on a cranberry juice cocktail to alleviate their symptoms, but, according to a Texas A&M Health Science Center urologist, drinking cranberry juice to treat a UTI is little more than an old wives' tale.