CURRENT NEWS

Overactive Bladder News

1. FDA approves new indication for drug to treat pediatric NDO patients

   Today, the U.S. Food and Drug Administration approved a new indication for Myrbetriq (mirabegron extended-release tablets) and Myrbetriq Granules (mirabegron for extended-release oral suspension) to treat neurogenic detrusor overactivity (NDO), a bladder dysfunction related to neurological impairment, in children ages three years and older.

2. App-based treatment for urinary incontinence was as effective as in-person treatment

   A mobile app designed to help women manage urinary incontinence was as effective as usual, in-person treatment of incontinence in primary care, according to new research from the Netherlands.

3. New approach to tame botulinum toxin for drug delivery

   While rare, botulism can cause paralysis and is potentially fatal. It is caused by nerve-damaging toxins produced by Clostridium botulinum -- the most potent toxins known.

4. Implantable smart wrap may help people who have under-active bladders

   An implantable smart wrap that fits safely and securely around the bladder may one day help people who have under-active bladders, a condition that hinders patients from urinating regularly and comfortably, according to an international team of researchers.

5. Study examines the side effects of Alzheimer's disease dementia drugs

   In a first of its kind study, a University of Houston researcher is examining two common drugs used for dementia in patients with Alzheimer's disease to determine the extent to which they don't mix well together and cause a cascading event of side effects, prompting the need for even more medications.

6. New study shows possible alternative pathway of SARS-CoV-2 infection in overactive bladder

   A new study published on the preprint server bioRxiv*, in June 2020, reports that the condition of overactive bladder (OAB) could be associated with a different route of infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent for COVID-19 disease.

7. Clinical trial evaluates effectiveness of spinal cord stimulation in patients with overactive bladder

   Keck Medicine of USC urologists are launching a clinical trial to evaluate the effectiveness of spinal cord stimulation in patients with an overactive bladder due to neurological conditions, such as a spinal cord injury or stroke, and idiopathic (unknown) causes.

8. Scientists identify chemicals in urine that are specific to overactive bladder

   Millions of people might eventually be spared the embarrassment and extreme isolation caused by wetting themselves, thanks to new research.

9. Effective non-surgical treatment options for urinary incontinence

   A common myth about urinary incontinence (the loss of bladder control or urinary leakage) in women is that surgery is your only option.

10. Lipid produced in response to cold helps reduce blood sugar

    Researchers based in Brazil, the United States and Germany have discovered that 12-HEPE, a lipid produced in response to cold by brown adipose tissue in the human body, helps reduce blood sugar. The results of their experiments with mice pave the way for new treatments for diabetes.